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Oxymorphone sold under the brand names Numorphan and Opana among others is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes, after oral administration it begins after about 30 minutes, and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets
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Buy Opana ER For sale online which is an oxymorphone hydrochloride extended-release tablets. Opana Er was approved in the year 2006 for the use in the management of moderate to severe pain. Opana Er is marketed currently by Endo Pharmaceuticals. Endo Pharmaceuticals is reformulation of the original product. It is designed with physicochemical properties intended to make the drug resistant to physical and chemical manipulation for abuse by snorting and injecting.
Also, while the reformulation of Opana ER was approved in the year 2011, the FDA determined that the drug did not meet the agency’s standards . Endo’s request to include a description of abuse-deterrent properties in product labeling.
Furthermore, Endo replaced the original formulation Opana ER with the new formulation in 2012. Opana ER also exposes users to risks of addiction, and abuse. Also, misuse of Opana ER can cause overdose and may lead to death. It is always advisable to examine patient’s risk before Opana ER is prescribed and the behaviour and conditions of the patient should be monitored. Also, in order to gain from the uses of Opana ER, it always good to follow the Risk Evaluation and Mitigation Strategy (REMS) of Opana ER offered by FDA. Buy Opana ER For sale online.
Opana ER Drug Information
Opana ER is well known for it life threatening, or fatal respiratory depression may occur as side effect effects of Opana ER if not taken as prescribed. So therefore, it is wise to monitor closely, especially when taking the Opana ER for the first time or dose increase. Also, Accidental ingestion of OPANA ER, especially by children, can result in fatal overdose of oxymorphone. Buy Opana ER For sale online.
Furthermore, if Opana ER is used in a very long time during pregnancy, it can result in neonatal opioid withdrawal syndrome. which may be life-threatening if not recognized and treated quickly. Opana ER has bad interactions with some substance. So therefore, avoid taking Opana ER after consuming alcohol or any product containing alcohol. This as result of the fact that, co-ingestion can result in fatal plasma oxymorphone levels.
More to that, continuous use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. Buy Opana ER For sale online.
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What is the Chemical Composition of Opana ER
Chemically Opana ER( Oxymorphone) is made up of 17 carbon atoms, 19 hydrogen molecules 1 Nitrogen molecule and 4 Oxygen atoms. Opana ER has C17H19NO4 as it chemical formula and has a molar of 301.3371 g/mol.
What Are The Medical Uses Of Opana ER
Opana ER is indicated for the relief of moderate to severe pain in patients requiring continuous, around-the-clock opioid treatment for an extended period of time. Limitations of uses of OPana ER is not intended for use as an as needed analgesic. Buy Opana ER For sale online.
In general, Opana ER can be use to treat people suffering form situations such as;
- Opana ER can also be use to treat and monitor renal function
What are the Side-effects of Opana ER
Opana ER has side effects if not taken in the right manner. Buy Opana ER For sale online.
Some of the side effects of Opana ER include;
- Addiction, Abuse, and Misuse
- Life Threatening Respiratory Depression
- Neonatal Opioid Withdrawal Syndrome
- Interactions with Benzodiazepines or Other CNS Depressants
- Anaphylaxis and angioedema
- Adrenal Insufficiency
- Severe Hypotension
- Gastrointestinal Adverse Reactions
- respiratory depression
- profound sedation
- dry mouth
What the Effect of Overdose Opana ER(Oxymorphone)
Just like any other opioids, Opana ER( Oxymorphone) over dosage is is characterized by some adverse effects some of which include;
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- sleepiness progressing to stupor or coma,
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- And sometimes slow heart rate and low blood pressure
Also, In a severe case of overdose, apnea , circulatory collapse, cardiac arrest and death can occur. Buy Opana ER For sale online and worry no more how much does Opana ER cost.
What is the Correct Dosage $ Administration of Opana ER
- It is always advisable to use the lowest effective dosage of Opana ER for the shortest duration that is recommended for the patient individual treatment. Buy Opana ER For sale online.
- Also, dosing is dosage of Opana ER is suppose to be individualised based on the degree of pain, patient response, prior analgesic experience, and risk factors for addiction, abuse, and misuse.
- Avoid taking Opana ER on an empty stomach. Always take it at least 1 hour prior to or 2 hours after eating.
- Furthermore, Opana ER tablet should be taken one tablet a a particular time. Always use enough water to ensure complete swallowing immediately after placing in the mouth.
- Also, for opioid-naïve and opioid non-tolerant patients, initiate treatment with 5 mg tablets orally every 12 hours.
- In addition, the dosage of Opana ER can be increased every 3 to 7 days by using the increment of 5 to 10 mg every 12 hours.
- Furthermore, avoid sharp discontinue of Opana ER if you are a physically dependent patient. This is because, rapid discontinuation of opioid analgesics may lead to serious withdrawal symptoms, uncontrolled pain, and suicide.
- Mild Hepatic Impairment: For opioid-naïve patients, initiate treatment with 5 mg and titrate slowly. For patients on prior opioid therapy, reduce starting dose by 50% and titrate slowly. Monitor for signs of respiratory and central nervous system depression. Buy Opana ER For sale online.
What is the interactions Of Opana ER with other Medicines
Buy Opana ER For sale online. Opana ER has different interaction with different medicines some of which beneficial while others leads to side effects of Opana ER.
- Avoid the interaction Opana ER and Antagonist and Partial Agonist Opioid Analgesics because they may reduce analgesic effect of OPANA ER or precipitate withdrawal symptoms.
- Interaction Opana ER and Monoamine Oxidase Inhibitors (MAOIs): Can potentiate the effects of oxymorphone.
- Also, using Opana ER with Serotonergic drugs continuously may lead to serotonin syndrome.
What is the best method to store Opana ER
We advise patients to store Opana ER in a secure place, preferably locked and out of the reach of children and other non-caregivers. Also, Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Buy Opana ER For sale online
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